The launch marks a fundamental shift in spatial biology — from 2D thin-section approaches that analyze partial cell layers to true 3D analysis that preserves the native organization of cells, ...
Researchers have developed a near-single-cell resolution spatial transcriptomic approach to study developmentally regulated RNA processes.
A new software tool, ovrlpy, improves quality control in spatial transcriptomics, a key technology in biomedical research. Developed by the Berlin Institute of Health at Charité (BIH) in international ...
Abstract: Recent advancements in spatial transcriptomics technology have enabled the capture of gene expression profiles while maintaining spatial information. Accurately identifying spatial ...
stFormer incorporates ligand genes within the spatial niche into transformer encoder of single-cell transcriptomics, and outputs gene embeddings specific to the intracellular context and spatial niche ...
aDivision of Rheumatology, Department of Internal Medicine, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, 510630, China bDepartment of Endocrinology and Metabolism, ...
Advancements in spatial perturbation transcriptomics (SPT) have revolutionized our understanding of cellular behavior in native tissue contexts by integrating spatial and perturbation data. However, ...
The interplay between cellular metabolism and immune function—immunometabolism—has emerged as a cornerstone of modern pathology (1). Immune cells are not static entities; they continuously adapt their ...
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