New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...
Two new studies uncover how DNA folding controls sperm cell development. Researchers identified proteins that rearrange genomic architecture, setting cellular memory and fate. This 3D genome mapping ...
Special proteins -- known as membrane transporters -- are key to the mobility of sperm cells. A research team has, with the aid of cryo-electron microscopy, succeeded in decoding the structure of such ...
A team led by University of Osaka researchers has developed a technique to generate testes from mouse embryonic stem cells ...
Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...
In human cells, DNA carries chemical or "epigenetic" marks that decide how genes will be used in different tissues. Yet in a ...
Neil Hunter, a professor in the Department of Microbiology and Molecular Genetics, has discovered a crucial step in how chromosomes stay connected during the development for egg cells and sperm, ...
Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...