A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

To study biological processes, scientists often take snapshots of the molecules in cells, such as proteins and nucleotides, at specific points in time. In spatial biology, they can leverage molecular ...

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

A new spatial transcriptomic approach captures the regulation of splicing and polyadenylation sites during pubescent brain development at near-single-cell resolution. An international collaboration, ...