It’s well established that some cases of amyotrophic lateral sclerosis (ALS) are caused by mutations that are inherited from a person’s parents — but a new study shows some cases of sporadic ALS may ...

As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully ...

For decades, the standard explanation for autoimmune diseases like rheumatoid arthritis has rested on two pillars: inherited ...

New research suggests that autoimmune diseases may be driven by DNA mutations in immune cells that remove the natural brakes ...

Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets for future precision medicine. Somatic genomics uncovers the outcomes of ...

Schizophrenia (SCZ) is a psychiatric disorder with onset in adulthood, and is thought to be triggered by some combination of environmental factors and genetics. However, the exact cause of the ...

What causes autoimmune disease? A new study finds that somatic mutations in immune checkpoint genes like PDL1 trigger the ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...

ctDNA as a biomarker in phase II study of tepotinib in advanced solid cancers with MET exon 14 skipping mutation or amplification (KCSG AL19-17). Characterization of molecular response and progression ...