Genes hold the recipe for proteins, which are made of amino acids. DNA only has four letters, or nucleotides, and each sequence of three nucleotide bases, or codon, encodes for one amino acid. There ...

Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

For example, there is a synonymous mutation in the chloride transmembrane cystic fibrosis transmembrane conductance regulator (CFTR) that slows down CFTR production and folding because it interacts ...