Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem ...

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to the stem cells responsible for maintaining and healing the intestine. The ...

Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory cells. Manipulating the enzyme OGDH ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...