Scientists in Singapore have developed a new oral compound designed to help people manage their weight by reducing how much ...

Plasma LDL-C concentrations can potentially be lowered either by inhibiting the synthesis of cholesterol by the tissues and/or driving the excretion of cholesterol from the body. Although blocking ...

A schematic illustration of the role of DHHC5 and CRYBG1 in controlling lacteal function and intestinal lipid absorption by maintaining the lipid raft association of VEGFR2. The proper functioning of ...

Individuals with metabolic dysfunction-associated steatotic liver disease (MASLD) had a higher rate of appearance of oral glucose — particularly during the first hour after a glucose load — and higher ...

Scientists at UCLA described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream. The finding might ...

A study published in the journal Protein & Cell details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid ...

A new preclinical study published in the journal Nature is demonstrating how fructose can alter cells in the small intestine, subsequently enhancing nutrient absorption and promoting weight gain. The ...

During drug development, researchers need to perform adequate nonclinical testing to ensure a drug’s safety and efficacy before starting clinical trials. An important aspect they must evaluate is a ...

Malabsorption refers to the reduced absorption of nutrients from the intestine into the bloodstream. It can affect the body’s ability to absorb all nutrients or some specific types of nutrients.