For decades, the idea of resetting the biological clock sounded more like speculative fiction than clinical strategy. The discovery of Yamanaka factors by Nobel laureate Shinya Yamanaka, which can ...

Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...

Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as ...