Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Scientists have engineered a tobacco relative to produce five psychedelic tryptamines, compounds normally scattered across ...

Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF. With a growing human population and rising living standards, demand for animal-derived ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, ...

Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA ...

Researchers discover a protein that connects GLP-1 drugs to long-term, broad genomic responses that can promote pancreatic ...

Colorectal cancer (CRC) arises from genetic and epigenetic alterations, including histone modifications. Unlike genetic changes, epigenetic ...

An ad hoc committee appointed by the National Academies to explore heritable genetic modifications of food animals. This committee will address methods for heritable genetic modifications and identify ...