Learn how small mutations in non-coding DNA can alter sex development in rodents.

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

A single DNA letter, inserted into a stretch of the genome that doesn’t code for any protein, was enough to turn genetically ...

Scientists have found new genetic causes for diabetes in babies—in a part of the genome that has historically been overlooked ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...