This article introduces the concepts of pooled variance and the central limit theorem, which are intended for establishing acceptance criteria for blend uniformity data of granular powder blends when ...

New technologies, such as NIR and Raman, enable online measurements of blending and content uniformity in the production of solid dosage forms. Advanced analytical instruments, such as near infrared ...

Additionally, Content Uniformity (CU), which relies heavily on the proper blend uniformity of the final pharmaceutical product, must be verified for product release. During the development process, ...