Nature

Bayesian Estimation and Maximum Likelihood Methods

Bayesian estimation and maximum likelihood methods represent two central paradigms in modern statistical inference. Bayesian estimation incorporates prior beliefs through Bayes’ theorem, updating ...
Medscape

FDA Changes Drug Trial Guidance: Experts Take Sides

The FDA has opened the door to the use of Bayesian statistical methods in clinical trials. The worry: Introducing ...
Morningstar

Professor Sarfaraz Niazi's Scientific Framework Adopted as FDA Modernizes Clinical Trial Evaluation Through Bayesian Methods

WASHINGTON, Jan. 20, 2026 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) has issued new draft guidance modernizing statistical methodologies used in clinical trials, formally recognizing ...
ascopubs.org

Comparative Study of Bayesian Information Borrowing Methods in Oncology Clinical Trials

Cobimetinib Plus Vemurafenib in Patients With Colorectal Cancer With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study We divided the borrowing ...
Opinion

How To Speed Up the Search for Cures Through a Change in Probability Theory

If the FDA follows through with the proposed guidelines, and they are not fatally twisted by pressure from the medical establishment and health care industry, it should bring fresh air and sunlight ...